SARS-COV-2是一种上呼吸系统的RNA病毒，截至2021年5月，在全球范围内引起超过300万人死亡，截至5月201日。迄今为止，SARS-COV-2突变对科学家造成重大挑战跟上疫苗开发和公共卫生措施的步伐。因此，鉴定来自患者的实验室样本分歧的有效方法非常有助于SARS-COV-2基因组学的文件。在这项研究中，我们提出了一种神经网络模型，可利用复发性和卷积单元直接参与尖峰蛋白的氨基酸序列并分类相应的片状。我们还将我们的模型的性能与来自蛋白质数据库预先培训的变压器（BERT）的双向编码器表示。我们的方法具有基于基于物种内分化的当前同源性提供了更加计算上的替代方案。

Blind image quality assessment (BIQA) remains challenging due to the diversity of distortion and image content variation, which complicate the distortion patterns crossing different scales and aggravate the difficulty of the regression problem for BIQA. However, existing BIQA methods often fail to consider multi-scale distortion patterns and image content, and little research has been done on learning strategies to make the regression model produce better performance. In this paper, we propose a simple yet effective Progressive Multi-Task Image Quality Assessment (PMT-IQA) model, which contains a multi-scale feature extraction module (MS) and a progressive multi-task learning module (PMT), to help the model learn complex distortion patterns and better optimize the regression issue to align with the law of human learning process from easy to hard. To verify the effectiveness of the proposed PMT-IQA model, we conduct experiments on four widely used public datasets, and the experimental results indicate that the performance of PMT-IQA is superior to the comparison approaches, and both MS and PMT modules improve the model's performance.

Given the increasingly intricate forms of partial differential equations (PDEs) in physics and related fields, computationally solving PDEs without analytic solutions inevitably suffers from the trade-off between accuracy and efficiency. Recent advances in neural operators, a kind of mesh-independent neural-network-based PDE solvers, have suggested the dawn of overcoming this challenge. In this emerging direction, Koopman neural operator (KNO) is a representative demonstration and outperforms other state-of-the-art alternatives in terms of accuracy and efficiency. Here we present KoopmanLab, a self-contained and user-friendly PyTorch module of the Koopman neural operator family for solving partial differential equations. Beyond the original version of KNO, we develop multiple new variants of KNO based on different neural network architectures to improve the general applicability of our module. These variants are validated by mesh-independent and long-term prediction experiments implemented on representative PDEs (e.g., the Navier-Stokes equation and the Bateman-Burgers equation) and ERA5 (i.e., one of the largest high-resolution data sets of global-scale climate fields). These demonstrations suggest the potential of KoopmanLab to be considered in diverse applications of partial differential equations.

Model bias triggered by long-tailed data has been widely studied. However, measure based on the number of samples cannot explicate three phenomena simultaneously: (1) Given enough data, the classification performance gain is marginal with additional samples. (2) Classification performance decays precipitously as the number of training samples decreases when there is insufficient data. (3) Model trained on sample-balanced datasets still has different biases for different classes. In this work, we define and quantify the semantic scale of classes, which is used to measure the feature diversity of classes. It is exciting to find experimentally that there is a marginal effect of semantic scale, which perfectly describes the first two phenomena. Further, the quantitative measurement of semantic scale imbalance is proposed, which can accurately reflect model bias on multiple datasets, even on sample-balanced data, revealing a novel perspective for the study of class imbalance. Due to the prevalence of semantic scale imbalance, we propose semantic-scale-balanced learning, including a general loss improvement scheme and a dynamic re-weighting training framework that overcomes the challenge of calculating semantic scales in real-time during iterations. Comprehensive experiments show that dynamic semantic-scale-balanced learning consistently enables the model to perform superiorly on large-scale long-tailed and non-long-tailed natural and medical datasets, which is a good starting point for mitigating the prevalent but unnoticed model bias.

CutMix is a vital augmentation strategy that determines the performance and generalization ability of vision transformers (ViTs). However, the inconsistency between the mixed images and the corresponding labels harms its efficacy. Existing CutMix variants tackle this problem by generating more consistent mixed images or more precise mixed labels, but inevitably introduce heavy training overhead or require extra information, undermining ease of use. To this end, we propose an efficient and effective Self-Motivated image Mixing method (SMMix), which motivates both image and label enhancement by the model under training itself. Specifically, we propose a max-min attention region mixing approach that enriches the attention-focused objects in the mixed images. Then, we introduce a fine-grained label assignment technique that co-trains the output tokens of mixed images with fine-grained supervision. Moreover, we devise a novel feature consistency constraint to align features from mixed and unmixed images. Due to the subtle designs of the self-motivated paradigm, our SMMix is significant in its smaller training overhead and better performance than other CutMix variants. In particular, SMMix improves the accuracy of DeiT-T/S, CaiT-XXS-24/36, and PVT-T/S/M/L by more than +1% on ImageNet-1k. The generalization capability of our method is also demonstrated on downstream tasks and out-of-distribution datasets. Code of this project is available at https://github.com/ChenMnZ/SMMix.

We present SODA: the first publicly available, million-scale high-quality social dialogue dataset. Using SODA, we train COSMO: a generalizable conversation agent outperforming previous best-performing agents on both in- and out-of-domain datasets. In contrast to most existing crowdsourced, small-scale dialogue corpora, we distill 1.5M socially-grounded dialogues from a pre-trained language model (InstructGPT; Ouyang et al., 2022). Dialogues are distilled by contextualizing social commonsense knowledge from a knowledge graph (Atomic10x; West et al., 2022). Human evaluation shows that dialogues in SODA are more consistent, specific, and (surprisingly) natural than prior human-authored datasets - e.g., DailyDialog (Li et al., 2017), BlendedSkillTalk (Smith et al., 2020). In addition, extensive evaluations show that COSMO is significantly more natural and consistent on unseen datasets than best-performing dialogue models - e.g., GODEL (Peng et al., 2022), BlenderBot (Roller et al., 2021), DialoGPT (Zhang et al., 2020). Furthermore, it is sometimes even preferred to the original human-written gold responses. We make our data, models, and code public.

We propose a novel task, G4C (Goal-driven Guidance Generation in Grounded Communication), for studying goal-driven and grounded natural language interactions. Specifically, we choose Dungeons and Dragons (D&D) -- a role-playing game consisting of multiple player characters and a Dungeon Master (DM) who collaborate to achieve a set of goals that are beneficial to the players -- as a testbed for this task. Here, each of the player characters is a student, with their own personas and abilities, and the DM is the teacher, an arbitrator of the rules of the world and responsible for assisting and guiding the students towards a global goal. We propose a theory-of-mind-inspired methodology for training such a DM with reinforcement learning (RL), where a DM: (1) learns to predict how the players will react to its utterances using a dataset of D&D dialogue transcripts; and (2) uses this prediction as a reward function providing feedback on how effective these utterances are at guiding the players towards a goal. Human and automated evaluations show that a DM trained with RL to generate guidance by incorporating a theory-of-mind of the players significantly improves the players' ability to achieve goals grounded in their shared world.

Label smoothing is a regularization technique widely used in supervised learning to improve the generalization of models on various tasks, such as image classification and machine translation. However, the effectiveness of label smoothing in multi-hop question answering (MHQA) has yet to be well studied. In this paper, we systematically analyze the role of label smoothing on various modules of MHQA and propose F1 smoothing, a novel label smoothing technique specifically designed for machine reading comprehension (MRC) tasks. We evaluate our method on the HotpotQA dataset and demonstrate its superiority over several strong baselines, including models that utilize complex attention mechanisms. Our results suggest that label smoothing can be effective in MHQA, but the choice of smoothing strategy can significantly affect performance.

Aiming at the current problems of theory-oriented,practice-light,and lack of innovation ability in the teaching of postgraduate software engineering courses,a multi-stage feedback teaching mode for software engineering postgraduates based on competition project_driven is proposed. The model is driven by the competition project,and implementing suggestions are given in terms of stage allocation of software engineering course tasks and ability cultivation,competition case design and process evaluation improvement,etc. Through the implementation of this teaching mode,students enthusiasm and initiative are expected to be stimulated,and the overall development of students professional skills and comprehension ability would be improved to meet the demand of society for software engineering technical talents.

We present POTATO, the Portable text annotation tool, a free, fully open-sourced annotation system that 1) supports labeling many types of text and multimodal data; 2) offers easy-to-configure features to maximize the productivity of both deployers and annotators (convenient templates for common ML/NLP tasks, active learning, keypress shortcuts, keyword highlights, tooltips); and 3) supports a high degree of customization (editable UI, inserting pre-screening questions, attention and qualification tests). Experiments over two annotation tasks suggest that POTATO improves labeling speed through its specially-designed productivity features, especially for long documents and complex tasks. POTATO is available at https://github.com/davidjurgens/potato and will continue to be updated.